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This framework integrated evidence through the following streams: (1) Tirzepatide compared to placebo (indirect comparison): In the absence of direct tirzepatide CV outcome placebo-controlled trials, these estimates were derived by bridging direct evidence from SURPASS-CVOT with pooled data from multiple GLP-1RA-placebo trials
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The reaction mixture was stirred continuously under a nitrogen atmosphere at room temperature for 3 days
Nutrient gaps : Slowed digestion and appetite reduction can lead to deficiencies in key nutrients especially iron, B-complex, vitamin D, magnesium, zinc, and antioxidants
The recommended daily allowance for folate is modest, at 400 g per day (, )
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